Twikis (twee' keez) are members of the dog family. They come in all colors, sizes and shapes, but most of them are small. Twikis tend to have gentle temperaments and make great family pets. They are also prolific breeders.

The first twiki was reportedly identified in 1999 near Auburn, Indiana. In 2007, they resurfaced in Melbourne, Australia. Shortly afterwards, sightings were reported in San Francisco, California and in Orlando, Florida.

Unlike domestic dogs which have 78 chromosomes arranged in 39 pairs, twikis have an extra pair of chromosomes that give them their unique online traits.